Автор: Diane J. Burgess Название: Injectable Dispersed Systems: Formulation, Processing, and Performance Издательство: CRC Press Год: 2005 ISBN: 978-0849336997 Серия: Drugs and the Pharmaceutical Sciences (Book 149) Язык: English Формат: pdf Размер: 16,2 mb Страниц: 688
With the increasing number of biopharmaceutical products, the emerging market for gene therapeutics, and the high proportion of small molecule new drug candidates that have very poor solubility, the need for parenteral dispersed system pharmaceuticals is growing rapidly.
This book serves as a current in-depth text for the design and manufacturing of parenteral dispersed systems. The fundamental physicochemical and biopharmaceutical principles governing dispersed systems are covered together with design, processing, product performance, characterization, quality assurance, and regulatory concerns. A unique and critically important element of this work is the inclusion of practical case studies together with didactic discussions. This approach allows the illustration of the application of dispersed systems technology to current formulation and processing problems and, therefore, this will be a useful reference text for industrial research and development scientists and will help them in making choices of appropriate dosage forms and consequent formulation strategies for these dosage forms.